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Haplogroup M18
In human mitochondrial genetics, Haplogroup M18 is a human mitochondrial DNA (mtDNA) haplogroup. It is an India-specific lineage.〔〔
==Origin==
M18 is a descendent of the macro-Haplogroup M (mtDNA) and an ancient Indian-specific variant of M.〔 Haplogroup M18 shares a common coding region mutation (12007) together with the M4, M30, M37 and M38 haplogroups from the root of haplogroup M (superhaplogroup M4'30).〔〔 M4′30 super-clade is the only clade that shares an intermediate lineage between 2 haplogroups, while the rest of all M lineages have originated independently from the root of macrohaplogroup M; thus supporting the idea of rapid dispersal of modern humans along the Asian coast after they left Africa, followed by a long period of isolation.〔
Awaiting further information from complete mtDNA sequences,
the haplogroup M18 was first defined by Metspalu et al., in 2004 by using the transversion at np 16318.〔 This was later revised by Thangaraj et al., in 2006. Currently, the haplogroup is characterized by two coding region mutations, 12498 and 15942, and an additional control region mutation 194.〔
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